Actress Debra Messing may join Robert De Niro in Warner Bros' upcoming mob drama Wise Guys.

Actress Debra Messing is in talks with Warner Bros. Studio for a role in Wise Guys.

Warner Bros apparently confirmed the crime drama Wise Guys with actor Robert De Niro in the lead role last August.

Rain Man's Barry Levinson will direct Warner Bros crime drama Wise Guys.

Actor Robert De Niro will be seen in a double role in Warner Bros' crime drama Wise Guys.

Warner Bros.' Wise Guys film's story follows Italian American crime bosses Vito Genovese and Frank Costello.

Based on true events, Wise Guys  will set in 1957, Vito Genovese tried ( and failed ) to assassinate Frank Costello, who was ultimately injured and attempted to retire from mafia.

Actress Debra Messing could play Bobbie, Frank Costello's wife, in Warner Bros' crime drama Wise Guys.

Actress Debra Messing previously seen in Netflix's comedy-drama, 13. 

Actress Debra Messing best known for NBC sitcom Will & Grace.

Actress Debra Messing has also won the Primetime Emmy Award for the NBC sitcom Will & Grace.